GB/T 38481-2020
ActiveDetermination of ultralow-frequency mutations for microorganisms—Duplex sequencing
微生物超低频突变测定 双重测序法
Application Summary AI generated
This standard specifies the duplex sequencing method for detecting ultralow-frequency mutations in microorganisms, down to frequencies as low as 10⁻⁷. It is applied in biotechnology and medical research contexts, such as monitoring rare genetic variants in microbial populations during drug resistance studies or cancer-related mutation analysis. The method is particularly useful for quality control in microbial fermentation processes and for assessing mutagenicity in environmental or industrial microbiology testing.
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