GB/T 21826-2025
ActiveChemicals—Test method of acute oral toxicity—Up-and-down-procedure（UDP）
化学品 急性经口毒性试验方法 上下增减剂量法（UDP）
Application Summary AI generated
This standard specifies the up-and-down procedure (UDP) for testing the acute oral toxicity of chemicals, providing a method to estimate the median lethal dose (LD50) using a sequential dosing approach with fewer animals. It is applied in chemical safety assessment, particularly for industrial chemicals, pesticides, and pharmaceuticals, to classify substances according to their acute toxicity hazard. The method is used in regulatory toxicology testing, such as for GHS classification and environmental risk evaluation.
Related Standards
GB/T 27852-2011
Chemicals--Biodegradation screening test--Biochemical oxygen demand
GB/T 27849-2011
Chemicals--Degradation screening test--Chemical oxygen demand
GB/T 27850-2011
Chemicals - Ready biodegradability - General considerations
GB/T 27846-2011
Chemicals--Measurement of viscosity using the H6ppler falling-ball viscometer
GB/T 27845-2011
Chemicals—Test method for particle-size analysis of soils
GB/T 27856-2011
Chemicals--Aerobic and anaerobic transformation in soil test
GB/T 27851-2011
Chemicals—Terrestrial plant test—Vegetative vigour test
GB/T 27854-2011
Chemicals--Soil microorganisms--Nitrogen transformation test
Transparency note: The application summary and key sentences on this page were automatically generated by AI from the standard's original text. This content has not been human-verified and should not be used for compliance or regulatory purposes. Always refer to the official standard document from the issuing authority.