GB/T 15670.21-2017

Active

Toxicological test methods for pesticides registration—Part 21: Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo

农药登记毒理学试验方法 第21部分:体内哺乳动物肝细胞程序外DNA合成(UDS)试验

Standard Type
GBT
ICS
65.100
CCS
B17
Status
Active
Issue Date
2017-07-12
Implementation
2018-02-01
Centralized Committee
农业农村部
Issuing Authority
中华人民共和国国家质量监督检验检疫总局、中国国家标准化管理委员会

Application Summary AI generated

This standard specifies the in vivo unscheduled DNA synthesis (UDS) test using mammalian liver cells to evaluate the genotoxic potential of pesticides. It is applied during the toxicological safety assessment required for pesticide registration in China, specifically to detect DNA damage and repair activity in liver cells after chemical exposure. The method helps determine whether a pesticide can induce DNA repair synthesis, providing critical data for regulatory risk assessment and product approval.

Related Standards

Transparency note: The application summary and key sentences on this page were automatically generated by AI from the standard's original text. This content has not been human-verified and should not be used for compliance or regulatory purposes. Always refer to the official standard document from the issuing authority.