GB/T 15670.21-2017
ActiveToxicological test methods for pesticides registration—Part 21: Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo
农药登记毒理学试验方法 第21部分:体内哺乳动物肝细胞程序外DNA合成(UDS)试验
Application Summary AI generated
This standard specifies the in vivo unscheduled DNA synthesis (UDS) test using mammalian liver cells to evaluate the genotoxic potential of pesticides. It is applied during the toxicological safety assessment required for pesticide registration in China, specifically to detect DNA damage and repair activity in liver cells after chemical exposure. The method helps determine whether a pesticide can induce DNA repair synthesis, providing critical data for regulatory risk assessment and product approval.
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