GB/T 45238-2025
ActiveChemicals—Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9)
化学品 用虹鳟肝S9亚细胞组分测定体外固有清除率试验
Application Summary AI generated
This standard specifies a laboratory method for determining the in vitro intrinsic clearance of chemicals using the S9 sub-cellular fraction derived from rainbow trout liver (RT-S9). It is applied in environmental toxicology and chemical safety assessment to predict the biotransformation and persistence of industrial chemicals, pesticides, or pharmaceuticals in aquatic organisms. The test supports regulatory evaluations under frameworks like REACH or Chinese chemical management, helping to estimate bioaccumulation potential in fish species.
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Transparency note: The application summary and key sentences on this page were automatically generated by AI from the standard's original text. This content has not been human-verified and should not be used for compliance or regulatory purposes. Always refer to the official standard document from the issuing authority.