GB/T 45221-2025

Active

Chemicals—EASZY assay—Detection of endorine active substances, acting through estrogen receptors, using tansgeic tg(cyp19a1b:GFP) zebrafish embryos

化学品 EASZY试验 利用转基因 tg(cyp19a1b:GFP)斑马鱼胚胎通过雌激素受体检测内分泌活性物质

Standard Type
GBT
ICS
13.300
CCS
A80
Status
Active
Issue Date
2025-01-24
Implementation
2025-05-01
Centralized Committee
国家标准委
Issuing Authority
国家市场监督管理总局、国家标准化管理委员会

Application Summary AI generated

This standard specifies an in vivo testing method using transgenic zebrafish embryos (tg(cyp19a1b:GFP)) to detect chemicals that act through estrogen receptors, enabling identification of endocrine-disrupting substances. It is applied in environmental safety assessments, particularly for evaluating industrial chemicals, pesticides, and pollutants for their potential to interfere with hormonal systems in aquatic organisms. The assay provides a standardized, high-throughput screening tool for regulatory compliance and risk assessment in ecotoxicology.

Related Standards

Transparency note: The application summary and key sentences on this page were automatically generated by AI from the standard's original text. This content has not been human-verified and should not be used for compliance or regulatory purposes. Always refer to the official standard document from the issuing authority.