GB/T 21826-2008
AbolishedChemicals - Test method of acute oral toxicity - Up and down procedure (UDP)
化学品 急性经口毒性试验方法 上下增减剂量法（UDP）
Application Summary AI generated
This standard specifies the up-and-down procedure (UDP) for determining the acute oral toxicity of chemicals, primarily used in the pharmaceutical, chemical, and pesticide industries. It is applied in laboratory testing to estimate the median lethal dose (LD50) of a substance through sequential dosing, reducing the number of animals required compared to traditional methods. The protocol is critical for safety assessments of industrial chemicals, drug candidates, and agrochemicals to classify their toxicity and guide regulatory compliance.
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